Radionuclide-(Lutetium)-Therapy-Service-Cancer-Treatment-Beacon-Hospital-Malaysia

Yttrium 90 (Y90) DOTATATE

Yttrium-90 (Y90) DOTATATE is a form of targeted internal radiotherapy used in the treatment of certain types of neuroendocrine tumours. It involves the use of a radioactive isotope called Yttrium-90, which is attached to a molecule called DOTATATE. This molecule specifically targets and binds to somatostatin receptors, which are often found in high numbers on the surface of neuroendocrine tumour cells.

The radioactive properties of yttrium-90 allow it to deliver radiation directly to the tumour cells, while minimizing damage to surrounding healthy tissues. The emitted radiation from yttrium-90 can penetrate a short distance into the tumour, delivering a high dose of radiation to the targeted cells.

Y90 DOTATATE therapy is typically administered through intravenous injection. Once inside the body, the DOTATATE molecule binds to the somatostatin receptors on the tumour cells, allowing the yttrium-90 to deliver radiation directly to the tumour, while minimizing damage to surrounding healthy tissues. The emitted radiation from yttrium-90 can penetrate a short distance into the tumour, delivering a high dose of radiation to the targeted cells. This targeted approach helps to destroy or shrink the tumour cells, reducing tumour size and alleviating symptoms associated with neuroendocrine tumours.

The goal of Y90 DOTATATE therapy is to destroy or shrink the tumour cells, thereby reducing tumour size and alleviating symptoms associated with the neuroendocrine tumours. It is often used in cases where the tumours have spread to other parts of the body and surgical removal is not feasible.

Y90 DOTATATE therapy has shown clinical effectiveness in reducing tumour size and improving symptoms in patients with neuroendocrine tumours. As with any medical treatment, it is important to discuss the potential benefits and risks with your healthcare provider to determine if Y90 DOTATATE therapy is appropriate for your specific situation.